As the Embrace Kids Foundation Endowed Chair in Pediatric Hematology/Oncology and Chief of the Division of Pediatric Hematology/Oncology I lead a group of nationally recognized physicians who provide the most advanced patient care. Dr. Cole received his medical degree from Weill Cornell College of Medicine and completed residency in pediatrics at Mount Sinai Medical Center followed by a fellowship at Memorial Sloan Kettering Cancer Center. While there, he trained in laboratory science, working in molecular pharmacology. His research efforts remain focused on developing new treatments to improve the lives of children and adolescents with blood disorders and cancer. Dr. Cole’s laboratory, funded by the National Institutes of Health, investigates why some patients suffer side effects of cancer treatment, while others do not. They have identified common genetic variants and specific dietary factors that increase the risk of experiencing side effects of anticancer therapies. Clinically, he has been actively involved on a global level in designing and conducting clinical trials for children diagnosed with leukemia or lymphoma, through his leadership or advisory roles in several cooperative groups including the Dana Farber Cancer Institute Acute Lymphoblastic Leukemia Consortium; The Consorcio Latinoamericano de Enfermedades Hemato-Oncology; gicas Peditricas; the Indian Pediatric Oncology Group; and the Children’s Oncology Group (COG). He has led multiple COG clinical trials testing innovative, targeted combination therapy for adolescents and young adults with relapsed or refractory Hodgkin lymphoma.
Clinical Interests:
Pediatric cancer; leukemia; lymphoma, and clinical trials
Cornell University BS in Neurobiology and Behavior
-
1989
Ithica,
NY
Cornell University Medical College, New York, NY, 1993
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1993
Ithica,
NY
Mount Sinai Medical Center
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1994
New York,
NY
Mount Sinai Medical Center
-
1996
New York,
NY
Memorial Sloan Kettering Cancer Center & The New York Hospital
-
1999
New York,
NY
| Title: | Methotrexate causes persistent deficits in memory and executive function in a juvenile animal model |
| Authors: | Wen J, Maxwell RR, Wolf AJ, Spira M, Gulinello ME, Cole PD |
| Publisher: | Neuropharmacology |
| Date: | 2018 |
| Issue: | |
| Description: |
| Title: | Brentuximab vedotin with Gemcitabine for Pediatric and Young Adult Patients with Relapsed or Refractory Hodgkin Lymphoma: A Children’s Oncology Group, Single-arm, Phase 1 / 2 Trial |
| Authors: | Cole PD, McCarten KM, Pei Q, Spira M, Metzger ML, Drachtman RA, Horton TM, Bush R, Blaney SM, Weigel BJ, Kelly KM |
| Publisher: | The Lancet Oncology 2018 |
| Date: | 2018 |
| Issue: | 9 |
| Description: |
| Title: | Refining Risk Classification in Childhood B Acute Lymphoblastic Leukemia: Results of DFCI ALL Consortium Protocol 05-001 |
| Authors: | Vrooman LM, Blonquist TM, Harris MH, Stevenson KE, Place AE, Hunt SK, O’Brien JE, Asselin BL, Athale UH, Clavell LA, Cole PD, Kelly KM, Laverdiere C, Leclerc J-M, Michon B, Schorin MA, Sulis ML, Welch JJG, Neuberg DS, Sallan SE, Silverman LB |
| Publisher: | Blood Advances |
| Date: | 2018 |
| Issue: | 12 |
| Description: |
| Title: | Prognostic Impact of Kinase-Activating Fusions and IKZF1 Gene Deletions in Pediatric High-Risk B-Lineage ALL |
| Authors: | Tran TH, Harris MH, Nguyen JV, Blonquist TM, Stevenson KE, Stonerock E, Asselin BL, Athale UH, Clavell LA, Cole PD, Kelly KM, Laverdiere C, Leclerc J-M, Michon B, Schorin MA, Welch JJG, Reshmi S, Neuberg DS, Sallan SE, Loh ML, Silverman, LB |
| Publisher: | Blood Advances |
| Date: | 2018 |
| Issue: | 5 |
| Description: |
| Title: | Effectiveness of Antibacterial Prophylaxis during Induction Chemotherapy in Children with Acute Lymphoblastic Leukemia |
| Authors: | Sulis ML, Blonquist TM, Athale UH, Clavell LA, Cole PD, Kelly KM, Laverdiere C, Leclerc JM, Michon B, Schorin MA, Welch JG, Neuberg DS, Sallan SE and Silverman LB |
| Publisher: | Pediatric Blood and Cancer |
| Date: | 2018 |
| Issue: | 5 |
| Description: |
| Title: | An investigation of toxicities and survival in Hispanic children and adolescents with ALL: Results from the Dana-Farber Cancer Institute ALL Consortium protocol 05-001 |
| Authors: | Kahn JM, Cole PD, Blonquist TM, Stevenson K, Jin Z, Barrera S, Davila R, Roberts E, Neuberg DS, Athale UH, Clavel LA, Laverdiere C, Leclerc J-M, Michon B, Schorin MA, Welch JJG, Sallan SE, Silverman LB, Kelly KM |
| Publisher: | Pediatric Blood and Cancer |
| Date: | 2017 |
| Issue: | |
| Description: |
| Title: | Liposomal Cytarabine Induces Less Neurocognitive Dysfunction than Intrathecal Methotrexate in an Animal Model |
| Authors: | Thomsen AM, Gulinello ME, Vijayanathan V, Wen J, Schmiegelow K, Cole PD |
| Publisher: | Journal of Pediatric Hematology / Oncology |
| Date: | 2017 |
| Issue: | 2 |
| Description: |
| Title: | Pharmacogenetic Predictors of Treatment-Related Toxicity among Children with Acute Lymphoblastic Leukemia |
| Authors: | Maxwell RR, Cole PD |
| Publisher: | Current Hematologic Malignancy Reports |
| Date: | 2017 |
| Issue: | 3 |
| Description: |
| Title: | A Thymidylate Synthase Polymorphism is Associated with Increased Risk for Bone Toxicity Among Children Treated for Acute Lymphoblastic Leukemia |
| Authors: | Finkelstein Y, Blonquist TM, Vijayanathan V, Stevenson KE, Neuberg DS, Silverman LB, Vrooman LM, Sallan SE, Cole PD |
| Publisher: | Pediatric Blood & Cancer |
| Date: | 2017 |
| Issue: | 7 |
| Description: |
| Title: | Feasibility of Baseline Neurocognitive Assessment using Cogstate During the First Month of Therapy for Childhood Leukemia |
| Authors: | Sands SA, Harel BT, Savone M, Kelly K, Vijayanathan V, Welch JG, Vrooman L, Silverman LB, Cole PD |
| Publisher: | Supportive Care in Cancer |
| Date: | 2016 |
| Issue: | |
| Description: |
| Title: | How variable is our delivery of information? A survey of medical providers assessing provider-driven patient teaching about oral chemotherapy regimens for pediatric patients with acute lymphoblastic leukemia |
| Authors: | Kahn J, Athale, UH, Clavell LA, Cole PD, Leclerc J-M, Laverdiere C, Michon B, Schorin MA, Welch JG, Sallan SE, Silverman LB, Kelly KM |
| Publisher: | Journal of Pediatric Health Care |
| Date: | 2016 |
| Issue: | |
| Description: |
| Title: | The Diet and Acute Lymphoblastic Leukemia Treatment (DALLT) Cohort Study: Rationale, Design, and Baseline Characteristics |
| Authors: | Ladas EJ, Orjuela M, Stevenson K, Cole PD, Lin M, Athale UH, Clavell LA, Leclerc J-M, Michon B, Schorin MA, Welch JG, Asselin B, Sallan S, Silverman LB, Kelly KM |
| Publisher: | Nutrition |
| Date: | 2016 |
| Issue: | |
| Description: |
| Title: | Asparaginase Erwinia chrysanthemi as a component of a multi-agent chemotherapeutic regimen for the treatment of patients with acute lymphoblastic leukemia who have developed hypersensitivity to E. coli-derived asparaginase |
| Authors: | Figueiredo L, Cole PD, Drachtman RA |
| Publisher: | Expert Rev Hematol |
| Date: | 2016 |
| Issue: | 3 |
| Description: |
| Title: | Long-term outcomes for children with acute lymphoblastic leukemia (ALL) treated on the Cancer Institute of New Jersey ALL trial (CINJALL) |
| Authors: | Drachtman RA, Masterson M, Shenkerman A, Vijayanathan V, Cole PD |
| Publisher: | Leukemia and Lymphoma 2016 |
| Date: | 2016 |
| Issue: | 10 |
| Description: |
| Title: | Predictors of thrombosis in children receiving therapy for acute lymphoblastic leukemia (ALL): Results from Dana-Farber Cancer Institute (DFCI) ALL Consortium trial 05-001. Pediatric Blood & Cancer. |
| Authors: | Athale UH, Flamand Y, Blonquist T, Steveson KE, Spira M, Asselin BL, Clavell LA, Cole PD, Kelly KM, Laverdiere C, Leclerc J-M, Michon B, Schorin MA, Welch JJG, Harris MH, Neuberg DS, Sallan SE, Silverman LB. |
| Publisher: | |
| Date: | 2022 |
| Issue: | |
| Description: | 2022; 00e29581. https://doi.org/10.1002/pbc.29581 |
| Title: | Durable remission for four pediatric patients with high-risk relapsed classical Hodgkin lymphoma treated with Brentuximab vedotin plus Gemcitabine but without autologous stem cell transplantation: a report from the Children’s Oncology Group. |
| Authors: | Buhtoiarov IN, Mba N, Sandos CD, McCarten KM, Metzger ML, Pei Q, Bush R, Baker K, Kelly KM, Cole PD. |
| Publisher: | |
| Date: | 2022 |
| Issue: | |
| Description: |
| Title: | Patterns of Initial Relapse from a Phase 3 Study of Response-Based Therapy for High-Risk Hodgkin Lymphoma (AHOD0831): A Report from the Children’s Oncology Group. |
| Authors: | Parikh RR, Kelly KM, Hodgson DC, Hoppe BS, McCarten KM, Pei Q, Cho SY, Schwartz C, Cole PD, Roberts K. |
| Publisher: | |
| Date: | 2021 |
| Issue: | |
| Description: |
| Title: | Well-being of Pediatric Hematology/Oncology Providers and Staff During the COVID-19 Pandemic in the New York and New Jersey Epicenter. |
| Authors: | Moerdler S, Steinberg D, Jin Z, Cole P, Levy A, Rosenthal S. |
| Publisher: | |
| Date: | 2021 |
| Issue: | |
| Description: |
| Title: | LAG-3 is expressed on a majority of tumor infiltrating lymphocytes in pediatric Hodgkin lymphoma, Leukemia & Lymphoma |
| Authors: | Scott Moerdler, Michelle Ewart, Debra L. Friedman, Kara Kelly, Qinglin Pei, Mou Peng, XingXing Zang & Peter D. |
| Publisher: | |
| Date: | 2020 |
| Issue: | |
| Description: |
| Title: | Severe vincristine-related neurotoxicity in five patients with pediatric acute lymphoblastic leukemia requiring discontinuation of vincristine: a description of long-term outcome |
| Authors: | Egan-Sherry D, Bhuta R, Cole PD, Gennarini LM, Kahn JM, Sulis ML, DeNardo BD, Welch JJG. |
| Publisher: | |
| Date: | 2021 |
| Issue: | |
| Description: |
| Title: | Associations between Race and Overall Survival in Pediatric Patients with Diffuse Large B Cell Lymphoma |
| Authors: | Khullar K, Plascak JJ, Drachtman R, Cole, PD, Parikh RR. |
| Publisher: | |
| Date: | 2021 |
| Issue: | |
| Description: |
| Title: | Associations between Race and Overall Survival in Pediatric Patients with Diffuse Large B Cell Lymphoma |
| Authors: | Khullar K, Plascak JJ, Drachtman R, Cole, PD, Parikh RR. |
| Publisher: | |
| Date: | 2021 |
| Issue: | |
| Description: |
| Title: | Biomarkers of Cognitive Impairment in Pediatric Cancer Survivors. Journal of Clinical Oncology |
| Authors: | Williams AM and Cole PD |
| Publisher: | |
| Date: | 2021 |
| Issue: | |
| Description: |
| Title: | Identification of Prognostic Factors in Childhood T-cell Acute Lymphoblastic Leukemia: Results from DFCI ALL Consortium Protocols |
| Authors: | Burns MA, Place AE, Stevenson KE, Gutiérrez A, Forrest S, Vrooman LM, Harris MH, Weinberg OK, Hunt SK, O’Brien JE, Asselin BL, Athale UH, Clavell LA, Cole PD, Gennarini LM, Kahn JM, Kelly KM, Laverdierre C, Leclerc J-M, Michon B, Schorin MA, Sulis ML, Welc |
| Publisher: | |
| Date: | 2021 |
| Issue: | |
| Description: |
| Title: | Efficacy and Toxicity of Pegaspargase and Calaspargase Pegol in Childhood Acute Lymphoblastic Leukemia/Lymphoma |
| Authors: | Vrooman LM, Blonquist TM, Stevenson KE, Supko JG, Hunt SK, Cronholm SM, Koch V, Kay-Green S, Athale UH, Clavell LA, Cole PD, Harris MH, Kelly KM, Laverdiere C, Leclerc J-M, Michon B, Place AE, Schorin MA, Welch JJG, Neuberg DS, Sallan SE, Silverman LB. |
| Publisher: | |
| Date: | 2021 |
| Issue: | |
| Description: |
| Title: | The protective effects of dietary intake of antioxidants and treatment-related toxicity in childhood leukemia: A Report from the DALLT Cohort |
| Authors: | Ladas EJ, Blonquist TM, Puligandla M, Orjuela M, Stevenson K, Cole PD, Athale UH, Clavell LA, Leclerc J-M, Laverdiere C, Michon B, Schorin MA, Welch JG, Asselin BL, Sallan SE, Silverman LB, Kelly KM |
| Publisher: | |
| Date: | 2020 |
| Issue: | |
| Description: |
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