ACCL1333

A study designed to evaluate the safety and efficacy of Apixaban for Thromboembolism Prevention versus No Systemic Anticoagulant Prophylaxis during Induction Chemotherapy in children with newly diagnosed Acute Lympho.

Type: Treatment

Principal Investigator: Richard Drachtman, MD

Trial is open for enrollment

• Rutgers Robert Wood Johnson Medical School
• Robert Wood Johnson University Hospital

ACURATE

Evaluation of the safety and efficacy of the Acurate valve for transcatheter aortic valve replacement (TAVR)

Type: Device trial

Principal Investigator: Mark Russo, MD

Trial is open for enrollment

For inquiries, call (732) 235-9215

• Rutgers Robert Wood Johnson Medical School
• Robert Wood Johnson University Hospital

AEGIS II

A phase 3, multi-center, double-blind, randomized, placebo-controlled, parallel-group study designed to investigate the efficacy and safety of CSL 112 (Apolipoprotein A-I: human) on reducing the risk of major adverse CV events in subjects with acute coronary syndrome (ACS) diagnosed with either ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI), including those managed with percutaneous coronary intervention (PCI) or medically managed.

Type: Treatment

Trial is open for enrollment

• RWJ University Hospital Somerset

ALIGN-AR

To evaluate the safety and effectiveness/performance of the Transfemoral JenaValve Pericardial TAVR System in the treatment of patients with symptomatic severe aortic regurgitation.

Type: Device trial

Principal Investigator: Mark Russo, MD

Trial is open for enrollment

• Rutgers Robert Wood Johnson Medical School
• Robert Wood Johnson University Hospital

ALIGN-AS

To evaluate the safety and effectiveness/performance of the Transfemoral JenaValve Pericardial TAVR System in the treatment of patients with symptomatic severe aortic stenosis.

Type: Device trial

Principal Investigator: Mark Russo, MD

Trial is open for enrollment

For inquiries, call (732) 235-9215

• Rutgers Robert Wood Johnson Medical School
• Robert Wood Johnson University Hospital

AMPLATZER™ Amulet™ Left Atrial Appendage Occluder Randomized Controlled Trial

A study designed to evaluate the safety and effectiveness of the AMPLATZER Amulet Left Atrial Appendage Occluder.

Trial is open for enrollment

• Cooperman Barnabas Medical Center

ARRAY 797-301

A phase 3, multinational, randomized, placebo-controlled study of ARRY-371797 in patients with symptomatic dilated cardiomyopathy due to a lamin A/C gene mutation.

Type: Drug trial

Principal Investigator: Saurabh Kapoor, MD

Trial is open for enrollment

• Newark Beth Israel Medical Center

Assessing the Normal Microbiome and Virome of the Lung: A Pilot Study

Trial is open for enrollment.

• Cooperman Barnabas Medical Center

Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation (ASAP-TOO)

Trial is open for enrollment.

• Cooperman Barnabas Medical Center

BiSpectral Index (BIS) Monitoring and Sedation Practices in Critically Ill Mechanically Ventilated Patients: A Single Center, Prospective, Randomized Control Trial

Trial is open for enrollment

• Cooperman Barnabas Medical Center

CIRT

A randomized clinical trial investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic syndrome that have had a heart attack or multiple coronary blockages.

Type: Drug trial

Principal Investigator: John B. Kostis, MD

Trial is open for enrollment

• Rutgers Robert Wood Johnson Medical School
• Robert Wood Johnson University Hospital

CLASP II TR

A study designed to evaluate the safety and effectiveness of transcatheter tricuspid valve repair with the Edwards PASCAL Transcatheter Valve Repair System and optimal medical therapy (OMT) compared to OMT alone in patients with tricuspid regurgitation.

Principal Investigator: Mark Russo, MD

Type: Device

This trial is open for enrollment

• Robert Wood Johnson University Hospital