Jan 5, 2021 Proactive Steps Against Pancreatic Cancer

Bob Rudnick is doing well after the detection and removal of a large cyst on his pancreas. “I’ve been lucky,” he says.
Bob Rudnick is doing well after the detection and removal of a large cyst on his pancreas. “I’ve been lucky,” he says.

Catching and evaluating growths on the pancreas can save lives.

At his routine physical exam in the fall of 2019, Bob Rudnick’s weigh-in showed that he had lost 13 pounds. The weight loss was unexplained, and his primary care physician was concerned. “He suggested I see a gastroenterologist,” says the Fairfield resident. “I’m lucky he did.”

An endoscopy and CT scan revealed that Bob, 82, had a cyst on his pancreas. That generated another referral, to a surgeon with expertise in pancreatic cysts and the risks they pose: Russell Langan, MD, Chief of Surgical Oncology and Hepatopancreatobiliary Surgery at Saint Barnabas Medical Center and surgical oncologist at Rutgers Cancer Institute of New Jersey.

“It was an exceedingly large cyst—10 centimeters,” Dr. Langan says. “We often operate when cysts are a quarter of that size.”

Yet the concern was less the cyst itself than its potential to become pancreatic cancer. “As a cyst grows, the risk of cancer increases,” Dr. Langan says, “and it’s an aggressive malignancy.”

Bob was indeed fortunate his cyst was caught. Although pancreatic cysts sometimes cause weight loss and other symptoms, they often escape notice. “I was feeling like my normal self,” he says.

HIDDEN DANGER

“Most pancreatic cysts are found incidentally when you get scanned for something else,” Dr. Langan says. “But we believe 15 percent of Americans have a pancreatic cyst.”

Some people with a pancreatic cyst have a precancerous subtype. Treatment in these cases, when administered in time, can prevent cancer from developing. Some cysts don’t require immediate surgery but should be monitored regularly for particular changes that may suggest an increased risk of malignancy.

“Once you have pancreatic cancer, even a small, early-stage cancer can threaten your life,” Dr. Langan says.

“We’ve made great strides in treating pancreatic cancer, but you could receive surgery, radiation and chemotherapy and this cancer still has the potential to come back. Therefore, high-risk pancreatic cysts should be removed prior to their developing into a pancreatic cancer.”

Still, many high-risk patients aren’t identified in a timely manner. “Not all practitioners are knowledgeable about cyst risks and guidelines for follow-up and interventions,” Dr. Langan says. “A lot of patients fall between the cracks. At Saint Barnabas Medical Center and RWJBarnabas Health, we have taken a strong approach with preventative medicine to catch things early.”

In Bob’s case, Dr. Langan recommended a surgery known as a Whipple procedure, a complex operation in which a portion of the pancreas is removed along with other parts of the gastrointestinal tract, including a piece of the small intestine, bile duct and gallbladder. The pancreas, bile duct and stomach are then reconstructed.

A DECISION TO MAKE

“Dr. Langan didn’t want to push me, but he tells it the way it is,” Bob says. “He told me, ‘You can live with the cyst, but the implication of what’s going on in there is not good.’”

Dr. Langan advised Bob to think about it for a week, during which time Bob got a second opinion from a former colleague of Dr. Langan’s in New York. That surgeon’s verdict was the same.

Bob was mindful of famous people who have developed or died from pancreatic cancer. Recent examples include Supreme Court Justice Ruth Bader Ginsburg, Congressman John Lewis and “Jeopardy” host Alex Trebek.

“Rather than live in fear, I thought, ‘I’ll have the operation,’” Bob says. “I elected to have Dr. Langan perform the surgery because I liked him and thought he was a good surgeon, and I could stay local rather than traipse into New York.”

“It’s important to have surgery at a high-volume center with high-volume surgeons,” Dr. Langan says. “At Saint Barnabas Medical Center, we check both those boxes.”

“It’s not just about the surgeon but having a team of highly trained and experienced nurses and other specialists built around care pathways that help ensure a safe operation and postoperative recovery. That has a positive impact on rates of complications and on survival.”

Bob’s delicate operation took place in November 2019. “Thank God the cyst turned out to be benign,” he says. He says he felt no pain after surgery other than soreness from the incision.

“Even my scar is hardly noticeable,” Bob says. “I’ve been lucky on all counts.”

To learn more about the Pancreatic Cyst Surveillance Program at Saint Barnabas Medical Center, call 973.322.6652 or visit www.rwjbh.org/sbmc.